surmeno's Bookmarks About "cardiovascular disease"

High Testosterone After Menopause Tied to Insulin Resistance, Heart Dise...

Not a large study, but demonstrating what we've long suspected: testosterone does carry risks. (free signup required to read)

by surmeno 2009-11-09 14:45 testosterone · insulin resistence · cardiovascular disease

http://www.medscape.com/viewarticle/711986 - cached - mail it - history

Hot Flushes, CHD, and Hormone Therapy in Postmenopausal Women

(free signup required to read)

by surmeno 2009-10-13 11:26 cardiovascular disease · hormones · hrts · risks · hotflashes

http://www.medscape.com/viewarticle/709345?src=rss - cached - mail it - history

Night Sweats in Postmenopausal Women Linked to Reduced 20-Year Mortality Rate

There's something missing in this one, some relationship they haven't quite twigged to OR recollection just isn't working well for a study method here. Doesn't make sense. (free signup required to read)

by surmeno 2009-10-03 09:52 hormones · menopause · hotflashes · cardiovascular disease · risks

http://cme.medscape.com/viewarticle/708987?src=cmenews&uac=104336HN - cached - mail it - history

Could transdermal estradiol+progesterone be a safer postmenopausal HRT?

Sadly, the full article is behind a paywall but even the abstract is interesting.

by surmeno 2009-09-29 13:08 hormones · hrts · risks · breast cancer · cardiovascular disease · blood clot

http://www.maturitas.org/article/S0378-5122(08)00204-1/abstract - cached - mail it - history

Low vitamin D may be deadly for older adults

by surmeno 2009-09-24 17:47 vitamins · nutrients · cardiovascular disease

http://www.reuters.com/article/healthNews/idUSTRE58N4PN20090924 - cached - mail it - history

Low vitamin D raises blood pressure in women

by surmeno 2009-09-24 15:14 vitamins · cardiovascular disease · risks · nutrients

http://www.reuters.com/article/healthNews/idUSTRE58M6HT20090923 - cached - mail it - history

Night Sweats in Postmenopausal Women Linked to Reduced 20-Year Mortality Rate

(free signup required to read)

by surmeno 2009-09-17 13:46 hotflashes · cardiovascular disease · risks · menopause · mortality

http://www.medscape.com/viewarticle/708988 - cached - mail it - history

Metabolic Syndrome in Women Linked to Increased Risk for PAD

(free signup required to read)

by surmeno 2009-09-16 10:25 cardiovascular disease · menopause · weight · metabolic syndrome · inflammation

http://www.medscape.com/viewarticle/708908?src=rss - cached - mail it - history

Characterizing Cardiovascular Risk in Women With Polycystic Ovary Syndrome

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by surmeno 2009-09-01 11:43 cardiovascular disease · weight · pcos · diabetes · metabolic syndrome

http://www.medscape.com/viewarticle/706188 - cached - mail it - history

Hyperlipidemia and Sexual Function in Premenopausal Women

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by surmeno 2009-08-11 18:43 cardiovascular disease · libido · lipids

http://www.medscape.com/viewarticle/706975?src=rss - cached - mail it - history

Flaxseed Reduces Blood Lipids

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by surmeno 2009-08-07 13:43 risks · cardiovascular disease · diet

http://www.medscape.com/viewarticle/706641?src=rss - cached - mail it - history

Oophorectomy Linked to Increased Risk for All-Cause Mortality

"Compared with ovarian conservation, bilateral oophorectomy at the time of hysterectomy for benign disease is associated with a decreased risk of breast and ovarian cancer but an increased risk of all-cause mortality, fatal and nonfatal coronary heart disease, and lung cancer," the study authors write. "In no analysis or age group was oophorectomy associated with increased survival."

by surmeno 2009-05-05 10:59 risks · cancer · cardiovascular disease · breast cancer · oophorectomy

http://www.medscape.com/viewarticle/702301 - cached - mail it - history

Diet, Nutrition, and Cancer

Talks about the caution needed in the face of many press releases that simplify study results to "this prevents cancer" when in fact the only major actually proven link is to obesity (30% increased risk) (free signup required to read)

by surmeno 2009-04-22 11:14 risks · cancer · cardiovascular disease · diet · breast cancer · weight

http://www.medscape.com/viewarticle/701722?src=rss - cached - mail it - history

Postmenopausal Tibolone Therapy

Good and detailed article sponsored by the manufacturer of this hrt. Also contains excellent review of hormone physiology. (free signup required to read)

by surmeno 2009-04-09 15:07 hormones · hrts · risks · cancer · cardiovascular disease · osteoporosis · drugs · estrogen · menopause · breast cancer · testosterone

http://www.medscape.com/viewarticle/548593_1 - cached - mail it - history

Lipid Profile Unfavorably Altered With Long-Term DHEA Treatment in GH...

Think that taking hormone precursors protects you from risk? Think again. (free signup required to read)

by surmeno 2009-04-09 13:40 hormones · risks · dhea · cardiovascular disease

http://www.medscape.com/viewarticle/590787?src=rss - cached - mail it - history

Aspirin for Primary Prevention of Cardiovascular Disease

women age 65 and older are likely to experience a net benefit from preventive low-dose aspirin therapy and should be considered for such therapy unless contraindicated. Most experts would recommend a dose of 81 mg to 100 mg daily, although higher doses may be required for patients with diabetes or established CVD. For most women below age 65, the WHS suggests that the risks of aspirin may outweigh the benefits. It is not known, however, whether subgroups of younger women at elevated CVD risk may benefit from aspirin or whether higher doses are needed for heart protection.

by surmeno 2009-04-04 15:30 risks · cardiovascular disease

http://www.medscape.com/viewarticle/590436?src=rss - cached - mail it - history

Experts Ponder Association Between Oophorectomy and Dementia

women who underwent a bilateral oophorectomy before menopause had close to a 2-fold increased risk for not only dementia but also parkinsonism, compared with those who did not have the surgery. The risk was also greater among those who had their ovaries removed and who stopped taking estrogen therapy before the age of 50 years. Women who underwent the procedure but who received estrogen-replacement therapy (ERT) until at least the age of 50 years returned to normal risk (free signup required to read)

by surmeno 2009-03-27 19:08 hormones · risks · cancer · osteoporosis · cardiovascular disease · menopause · estrogen · breast cancer · testosterone · brain · depression

http://www.medscape.com/viewarticle/590202?src=rss - cached - mail it - history

Raloxifene Associated With Thrombosis, Fatal Stroke in Postmenopausal Women

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by surmeno 2009-01-14 19:47 hrts · cardiovascular disease · risks

http://www.medscape.com/viewarticle/586668?src=rss - cached - mail it - history

Preventive Bilateral Oophorectomy Ups CV Mortality

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by surmeno 2009-01-14 19:20 risks · hormones · cardiovascular disease · oophorectomy

http://www.medscape.com/viewarticle/586781?src=rss - cached - mail it - history

Oophorectomy and CV Mortality

A new study has found that women who underwent preventive bilateral oophorectomy--removal of both ovaries--before the age of 45 were at increased risk of cardiovascular death some 20 to 30 years later [1]. But the results also show that this increased mortality can be attenuated by estrogen treatment (free signup required to read)

by surmeno 2009-01-13 14:41 risks · hormones · cardiovascular disease · oophorectomy

http://www.medscape.com/viewarticle/586719 - cached - mail it - history

Hormone Therapy Regimen, Route of Administration May Be Linked to MI Risk

"Unopposed estrogen was not associated with the risk of MI and was not significantly different from the risk with cyclic combined therapy...Furthermore, significantly lower MI risk was observed with dermal delivery compared to oral unopposed estrogen therapy..." (free signup required to read)

by surmeno 2008-12-09 13:31 cardiovascular disease · risks · hrts

http://www.medscape.com/viewarticle/584936?src=rss - cached - mail it - history

Hormone Cream May Aid Menopausal Symptoms

Finally the compounders strike back with a study of their own on the effects of transdermal compounded cream hrts (free signup required to read)

by surmeno 2008-11-21 14:30 risks · hrts · cardiovascular disease

http://www.medscape.com/viewarticle/583975?src=rss - cached - mail it - history

Bisphosphonates and atrial fibrillation

This describes a potential correlation with no (yet) established causation. Women with atrial fib thinking of using a bisphosphonate or who develop atrial fib while using one should take this information to their cardiologist.

by surmeno 2008-11-13 11:53 drugs · osteoporosis · cardiovascular disease

http://www.drugs.com/fda/update-early-communication-bisphosphonates-marketed-alendronate-fosamax-fosamax-plus-d-etidrona... - cached - mail it - history

Mixed Findings Cast Doubt on HRT Timing Hypothesis

This study does not distinguish route-related effects, which may be affecting their conclusions (free signup required to read)

by surmeno 2008-11-07 17:51 menopause · cardiovascular disease · cardiolipids

http://www.medscape.com/viewarticle/583208?src=rss - cached - mail it - history

Danish study finds HRT does not raise heart attack

More support for the lower cardiovascular risk profile of transdermals over orals

by surmeno 2008-10-01 12:16 hormones · risks · hrts · cardiovascular disease · route

http://www.reuters.com/articlePrint?articleId=USTRE48T8RI20080930 - cached - mail it - history

Selecting Menopausal Estrogen Therapy: Oral or Transdermal?

Excellent overview of factors affected by route of hrt delivery (free signup required to read)

by surmeno 2008-09-22 18:40 hormones · risks · hrts · cardiovascular disease · estrogen · testosterone · route · metabolic syndrome · diabetes

http://www.medscape.com/viewprogram/17277_pnt - cached - mail it - history

Treatment for Postmenopausal Women Reviewed

Good summary of routine care (albeit for women in natural meno) recommendations for menopausal women. (free signup required to read)

by surmeno 2008-09-02 19:05 menopause · risks · hrts · cardiovascular disease · prevention · testing

http://www.medscape.com/viewarticle/579943?src=rss - cached - mail it - history

Tibolone Decreases Fracture, Breast Cancer, but Doubles Stroke Risk

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by surmeno 2008-08-15 19:21 cancer · breast cancer · osteoporosis · bonedensity · cardiovascular disease · stroke · risks

http://www.medscape.com/viewarticle/579153?src=rss - cached - mail it - history

Jump in CV Risk With Menopause Tied to Hormonally Mediated MetS

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by surmeno 2008-07-29 18:45 hormones · risks · cardiovascular disease · estrogen · testosterone · metabolic syndrome

http://www.medscape.com/viewarticle/578211?src=rss - cached - mail it - history

NAMS menopause guidelines statement

This is the updated guidelines version that spells out who/how long/why and debunks many of the recent anti-hrt myths following on WHI (pdf download)

by surmeno 2008-07-21 15:10 hormones · hrts · risks · menopause · estrogen · cancer · osteoporosis · cardiovascular disease · a1a

http://www.menopause.org/PSHT08.pdf - cached - mail it - history

Cholesterol indicates if HRT would be heart-safe

women whose ratio of LDL ("bad") cholesterol to HDL ("good") cholesterol came to less than 2.5 had no increased risk of a heart attack or angina while using estrogen alone or with progesterone. By contrast, a ratio of 2.5 or higher was associated with a 73 percent higher likelihood of heart-related illness.

by surmeno 2008-06-16 14:43 cardiovascular disease · hrts

http://www.reuters.com/articlePrint?articleId=USKUA66396720080616 - cached - mail it - history

HRT Risk and Lipids

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by surmeno 2008-05-28 23:20 cardiovascular disease · risks · hrts

http://www.medscape.com/viewarticle/575209?src=rss - cached - mail it - history

Transdermal Estrogen Does Not Up Risk of Venous Thromboembolism?

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by surmeno 2008-05-27 19:29 risks · cardiovascular disease · hrts · route · oral · transdermal · clot

http://www.medscape.com/viewarticle/575009?src=rss - cached - mail it - history

FDA panel rejects testosterone patch for women on safety grounds

by surmeno 2008-05-24 10:49 testosterone · hrts · risks · cardiovascular disease

http://bmj.bmjjournals.com/cgi/content/full/329/7479/1363 - cached - mail it - history

Postmenopausal Status May Increase Risk for the Metabolic Syndrome

Note that this represents a correlation, with the exact causation not yet defined. (free signup required to read)

by surmeno 2008-05-24 00:47 metabolic syndrome · cardiovascular disease · metabolism · insulin resistence · weight · risks

http://www.medscape.com/viewarticle/574891 - cached - mail it - history

Oral hormone therapy pills double clot risk

by surmeno 2008-05-23 13:30 hormones · hrts · risks · clot · cardiovascular disease · route · oral

http://www.reuters.com/articlePrint?articleId=USL2293658720080522 - cached - mail it - history

Hormone therapy safe in early menopause

Repudiates the sweeping recommendation that women shouldn't use hrts that came out of the Women's Health Initiative aftermath.

by surmeno 2008-05-20 00:40 risks · hrts · hormones · cardiovascular disease · cancer · breast cancer · whi

http://www.reuters.com/articlePrint?articleId=USL1915748520080520 - cached - mail it - history

Calcium Ups MI Risk

Careful reading shows this is not reason to panic or to stop taking calcium for bones (free signup required to read)

by surmeno 2008-03-28 10:06 osteoporosis · cardiovascular disease · minerals · nutrients

http://www.medscape.com/viewarticle/568940 - cached - mail it - history

Estrogen, Medroxyprogesterone Acetate, Endothelial Function and Biomarkers of Cardiovascular Risk in Young Women

data suggest that acute MPA administration negates the beneficial effects of estradiol on endothelium-dependent vasodilation in young women (abstract only)

by surmeno 2008-03-10 19:31 cardiovascular disease · hormones · risks · progestin

http://www.ncbi.nlm.nih.gov/pubmed/18281378?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_R... - cached - mail it - history

Endothelial function across an oral contraceptive cycle in women using levonorgestrel and ethinyl estradiol

results suggest that levonorgestrel may antagonize the activity of ethinyl estradiol [on vascular lining]--in other words, CV risk may be a function of the progestin, not the estrogen (abstract)

by surmeno 2008-03-10 19:30 cardiovascular disease · risks · hrts · progestin

http://www.ncbi.nlm.nih.gov/pubmed/17277029?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_R... - cached - mail it - history

Beneficial Effect of Hormone Therapy on Mortality and Heart Disease

The window of opportunity for the maximal beneficial effect of HT on total mortality and CHD appears to be when HT is initiated within 6 years of menopause and/or before age 60, and continued for 5 years or more. The absolute risks associated with HT are low and even rarer (<1 additional event/1,000 women) in women younger than age 60 or within 5 years after menopause when initiating HT. The risks associated with ET alone are negligible. (free signup required to read)

by surmeno 2008-02-29 19:46 cardiovascular disease · risks · hrts · menopause

http://www.medscape.com/viewarticle/569935?src=rss - cached - mail it - history

Sex Hormone Levels Predict Atherosclerosis Progression in Women

Further defining the role estrogen plays in cardiovascular disease (free signup required to read)

by surmeno 2008-02-28 13:29 cardiovascular disease · risks · estrogen

http://www.medscape.com/viewarticle/570779?src=rss - cached - mail it - history

Slow Walking Speed Predicts Stroke Risk in Postmenopausal Women

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by surmeno 2008-02-28 12:42 cardiovascular disease · risks · exercise

http://www.medscape.com/viewarticle/570745?src=rss - cached - mail it - history

Differential Effects of Oral and Transdermal Estrogen/Progesterone Regimens on Sensitivity to Activated Protein C Among Postmeno

full text article

by surmeno 2008-02-27 13:16 cardiovascular disease · risks · estrogen · route

http://atvb.ahajournals.org/cgi/content/full/23/9/1671 - cached - mail it - history

Effect of Oral and Transdermal Estrogen Replacement Therapy on Hemostatic Variables Associated With Venous Thrombosis

abstract

by surmeno 2008-02-27 13:12 cardiovascular disease · risks · estrogen · route · clot

http://atvb.ahajournals.org/cgi/content/abstract/23/6/1116 - cached - mail it - history

Prothrombotic Mutations, Hormone Therapy, and Venous Thromboembolism Among Postmenopausal Women: Impact of the Route of Estrogen

abstract

by surmeno 2008-02-27 13:10 route · estrogen · cardiovascular disease · risks · clot

http://www.circ.ahajournals.org/cgi/content/abstract/112/22/3495 - cached - mail it - history

Obesity and risk of venous thromboembolism among postmenopausal women

abstract

by surmeno 2008-02-27 13:08 cardiovascular disease · estrogen · route · weight · clot · risks

http://www.ingentaconnect.com/content/bsc/jth/2006/00000004/00000006/art00017?token=00381252482f3f3b2c6a573d257025255323... - cached - mail it - history

Transdermal Estrogen Therapy Not Linked to Venous Thromboembolism

article; free signup required to read

by surmeno 2008-02-27 13:01 cardiovascular disease · estrogen · route · clot

http://www.medscape.com/viewarticle/459782 - cached - mail it - history

Effects of Transdermal Estrogen Replacement Therapy on Cardiovascular Risk Factors

abstract

by surmeno 2008-02-27 13:00 cardiovascular disease · route · estrogen

http://www.ingentaconnect.com/content/adis/end/2006/00000005/00000001/art00005 - cached - mail it - history

Postmenopausal Systemic Hormone Therapy: Putting Risks Into Perspective

Excellent evaluation by National Association of Nurse Practitioners in Women's Health and North American Menopause Society presenters (funded by Wyeth) looking at risks of using hrt (free signup required to read)

by surmeno 2008-01-31 19:28 risks · cardiovascular disease · osteoporosis · cancer · hrts · hormones

http://www.medscape.com/viewprogram/8663_pnt - cached - mail it - history

Vascular events in healthy older women receiving calcium supplementation: randomised controlled trial

This is the actual study on which the "calcium gives you heart attacks" headlines are based upon.

by surmeno 2008-01-23 17:25 cardiovascular disease · osteoporosis · nutrients · vitamins · lipids

http://www.bmj.com/cgi/content/full/bmj.39440.525752.BEv1 - cached - mail it - history

Analysis Shows No Excess Cardiovascular Risk from Hormone Replacement Therapy for Most Patients

young women in early menopause may not only have no increased cardiovascular risk from the therapy, but may indeed show benefit in the future

by surmeno 2008-01-07 17:34 cardiovascular disease · hormones · risks · estrogen · menopause

http://www.aace.com/newsroom/press/2008/index.php?r=20080102-1 - cached - mail it - history

Endocrinologist Association Encourages HRT in Younger Women

The American Association of Clinical Endocrinologists (AACE) has released a statement on hormone replacement therapy (HRT) and cardiovascular risk, emphasizing that HRT does not appear harmful in younger women in early menopause and may indeed be beneficial in this group

by surmeno 2008-01-07 17:34 cardiovascular disease · hormones · estrogen · menopause · risks

http://www.medscape.com/viewarticle/568354?src=rss - cached - mail it - history

Oral Contraceptives Linked to Increased Carotid Plaque

I wonder if this can be extended to combined hrts, which are lower dose but still can contain the same hormones. It's certainly a risk to be aware of. (free signup required to read)

by surmeno 2007-11-09 14:59 risks · cardiovascular disease

http://www.medscape.com/viewarticle/565581?src=rss - cached - mail it - history

Vitamin E May Protect Against Venous Thromboembolism in Women

This is highly pertinent given how hrt (esp. orals) raises clot risk in the first year of use. Note also the comments at the very end of the summary bullet points about Factor V Leiden and vitamin E. (free signup required to read)

by surmeno 2007-09-12 21:57 blood clot · cardiovascular disease

http://www.medscape.com/viewarticle/562707?src=rss - cached - mail it - history

Plant compounds blunt menopausal effects in rats

Women who enter menopause often develop high blood pressure, insulin resistance (a risk factor for type 2 diabetes), and memory loss.

by surmeno 2007-08-15 20:54 menopause · cardiovascular disease · metabolic syndrome · phytoestrogen

http://today.reuters.com/misc/PrinterFriendlyPopup.aspx?type=healthNews&storyID=2007-08-16T000623Z_01_SCH600361_RTRUKOC_... - cached - mail it - history

Estrogen loss contributes to obesity, high BP

Remember: this is just a rat study, but it does back up many women's experience with menopause and risk factors

by surmeno 2007-08-13 23:01 hormones · cardiovascular disease · weight · metabolism

http://today.reuters.com/misc/PrinterFriendlyPopup.aspx?type=healthNews&storyID=2007-08-13T162725Z_01_COL358957_RTRUKOC_... - cached - mail it - history

Study Supports HRT Use for Short Term, but Little Benefit in Older Women

Excellent discussion of the implications of hrt use and how women got a raw deal from the WHI panic. And excellent read. (free signup requited)

by surmeno 2007-07-16 18:03 hormones · hrts · risks · cardiovascular disease · menopause

http://www.medscape.com/viewarticle/559816?src=rss - cached - mail it - history

Hormone Therapy Safer in Younger Women? A Best Evidence Review

From JAMA, this opinion piece is likely to be of significant influence on doctors. Most worrisome for us, it doesn't take surgical meno into account and it states that some benefits should not be considered as countering risks.

by surmeno 2007-07-11 12:39 whi · menopause · hrts · risks · cardiovascular disease

http://www.medscape.com/viewarticle/559366 - cached - mail it - history

How NIH Misread Hormone Study in 2002 - WSJ.com

News analysis of the original WHI study cancellation and how the results have been reinterpreted with time.

by surmeno 2007-07-09 10:52 hormones · hrts · risks · cardiovascular disease · whi

http://online.wsj.com/article/SB118394176612760522.html - cached - mail it - history

Estrogen-Only Hormone Replacement Therapy May Lower Coronary Artery Disease

younger postmenopausal women treated with estrogen-only hormone replacement therapy (HRT) had significantly less coronary artery calcification than their counterparts taking placebo. (free signup required)

by surmeno 2007-06-22 16:34 cardiovascular disease · hrts · risks · estrogen

http://www.medscape.com/viewarticle/558657 - cached - mail it - history

Mediterranean Diet Rich in Olive Oil and Walnuts Protects Against Oxidative Damage

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by surmeno 2007-06-19 21:48 cardiovascular disease · diet · nutrients

http://www.medscape.com/viewarticle/558238?src=mp - cached - mail it - history

Hormone Therapy Given Closer to Menopause Onset Is Safest

I'm glad to see this rethinking of the data and the issuance of a more nuanced statement. (free signup required)

by surmeno 2007-04-11 14:39 cardiovascular disease · hrts · risks · whi

http://www.medscape.com/viewarticle/554659?src=mp - cached - mail it - history

Cardiovascular disease effects: estrogen +/- MPA

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by surmeno 2007-04-09 20:53 cardiovascular disease · estrogen · hrts · risks

http://www.medscape.com/viewarticle/553792_print - cached - mail it - history

Hot Flashes Are Associated With Ambulatory Systolic Hypertension

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by surmeno 2007-04-04 12:22 cardiovascular disease · hormones · risks · hotflashes · hypertension · blood pressure · brain

http://www.medscape.com/viewarticle/554149 - cached - mail it - history

Timing of Estrogen Therapy Determines Anti-Stroke Benefit

free signup required

by surmeno 2007-04-04 12:10 risks · cardiovascular disease · estrogen · stroke · survival

http://www.medscape.com/viewarticle/554145 - cached - mail it - history

Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions

Although this is a mouse study, it suggests that risks are indeed related to the time of initiation of estrogen supplementation.

by surmeno 2007-03-27 10:43 hormones · hrts · risks · cardiovascular disease · inflammation

http://www.pnas.org/cgi/content/abstract/0610394104v1 - cached - mail it - history

CDEP: Lipid Spike Seen When Hormone Therapy Stops - CME Teaching Brief® - MedPage Today

by surmeno 2007-03-22 23:22 cardiovascular disease · cardiolipids · hrts · risks

http://www.medpagetoday.com/OBGYN/Menopause/tb/5175 - cached - mail it - history

Healthy Diet Reduces Risk for Insulin Resistance and Metabolic Syndrome

"The current findings indicate that a dietary pattern characterized by high consumption of fruit, vegetables, poultry, and legumes is associated with reduced risk of insulin resistance and the metabolic syndrome in Tehrani female teachers," the authors conclude. "In contrast, a dietary pattern with high amounts of refined grains, red meat, butter, processed meat, and high-fat dairy products and low amounts of vegetables and low-fat dairy products is associated with a greater risk of the metabolic syndrome." (free signup required)

by surmeno 2007-03-15 13:51 diet · nutrition · cardiovascular disease · diabetes · metabolic syndrome · weight

http://www.medscape.com/viewarticle/553589?rss - cached - mail it - history

Oral, not Transdermal, Estrogen Increases Risk for VTE in Women

(free signup required)

by surmeno 2007-02-28 12:42 hrts · cardiovascular disease · risks · clot

http://www.medscape.com/viewarticle/552778?rss - cached - mail it - history

High Cholesterol Linked With Stroke Even in Healthy Women

That means even when you're fine, you should really watch your cholesterol, and by approaching low cholesterol levels, you may prevent risk for ischemic stroke. (free signup required)

by surmeno 2007-02-28 10:17 cardiovascular disease · diet · risks

http://www.medscape.com/viewarticle/552551?src=mp - cached - mail it - history

Comparative effects of estrogens plus androgens and tibolone on bone, lipid pattern and sexuality in postmenopausal women

The combined regimen of androgens and ERT increased vertebral bone mass and enhance sexual activity in postmenopausal women equal to that of tibolone and to a greater extent than ERT alone; its effects on lipids, however, are clearly adverse.

by surmeno 2007-02-12 16:07 hrts · hormones · risks · osteoporosis · cardiovascular disease · testosterone · estrogen · libido

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10714911&dopt=Abstract - cached - mail it - history

Effect of Transdermal Estradiol and Oral Conjugated Estrogen on C-Reactive Protein in Retinoid-Placebo Trial in Healthy Women -- Decensi et al. 106 (10): 1224 -- Circulation

In contrast to oral CEE, transdermal E2 does not elevate CRP levels up to 12 months of treatment.

by surmeno 2007-02-12 15:59 hormones · risks · cardiovascular disease · hrts · estrogen

http://circ.ahajournals.org/cgi/content/full/106/10/1224 - cached - mail it - history

Discontinuation of a clinical trial of Livial® (tibolone)

by surmeno 2007-02-12 15:35 hrts · uk · risks · cardiovascular disease

http://www.dkma.dk/1024/visUKLSArtikel.asp?artikelID=8196 - cached - mail it - history

Higher Air Pollution Levels Increase Risk for CV Events in Women

(free signup required)

by surmeno 2007-02-05 18:32 cardiovascular disease · environment · risks

http://www.medscape.com/viewarticle/551686?rss - cached - mail it - history

Transdermal Estrogen Suggested for Women With Metabolic Syndrome

While both oral and transdermal estrogen are beneficial for symptomatic postmenstrual women with the metabolic syndrome, transdermal therapy is preferable because oral therapy may worsen insulin resistance and adipocytokine parameters. (free signup required)

by surmeno 2007-01-17 14:51 hormones · hrts · pcos · cardiovascular disease · metabolism · diabetes · insulin resistence · risks · route

http://www.medscape.com/viewarticle/550371 - cached - mail it - history

Fight Cholesterol - 10 Top Foods To Help You Fight High Cholesterol

by surmeno 2007-01-14 11:25 diet · nutrition · cardiovascular disease · vitamins

http://www.fightcholesterol.org/nutrition/10-top-foods-to-help-you-fight-high-cholesterol.html - cached - mail it - history

Joint Symptoms and Other Adverse Effects of Aromatase Inhibitors

Of 612 women who responded, nearly all (96%) reported 1 or more adverse effects. About 30% of women reported discontinuing therapy, most of them (87%) because of intolerable adverse events and 47% because of joint-related problems. More than half of the respondents reported stroke, cough, swelling of arms and legs, flulike symptoms, and anxiety. Other effects included vaginal atrophy and dryness, a rise in cholesterol levels, and general pain. The full report and comments from respondents are available online. (free signup required)

by surmeno 2007-01-02 20:01 hormones · risks · cardiovascular disease · arthritis · osteoarthritis · joint pains · vaginal atrophy

http://www.medscape.com/viewarticle/549822?src=mp - cached - mail it - history

Exercise in the Age of Evidence-Based Medicine: A Clinical Update

How much exercise is enough? This powerpoint transcript is a little chatty, but provides some fairly concrete answers. (free signup required)

by surmeno 2006-12-26 21:53 exercise · cardiovascular disease · risks

http://www.medscape.com/viewprogram/6375_pnt - cached - mail it - history

Menopause: Cause or Consequence

Interesting commentary that questions whether, instead of menopause driving cardiovascular disease risk, CVD might drive some aspects of menopause. Not sure how this plays out in surgical meno, but it's worth watching as research develops. (free signup required)

by surmeno 2006-12-23 11:25 cardiovascular disease · risks · menopause

http://www.medscape.com/viewarticle/549693?rss - cached - mail it - history

NHLBI Women's Health Initiative (WHI)

Home page of the (in)famous study

by surmeno 2006-12-15 12:41 hrts · hormones · risks · cancer · hysterectomy · cardiovascular disease · menopause · whi

http://www.nhlbi.nih.gov/whi/ - cached - mail it - history

Hormone Replacement Therapy and Cardioprotection: The End of the Tale? -- ROSANO et al. 997 (1): 351 -- Annals of the New York Academy of Sciences

by surmeno 2006-12-05 12:51 hrts · cardiovascular disease · menopause · risks

http://www.annalsnyas.org/cgi/content/abstract/997/1/351 - cached - mail it - history

Prophylactic Oophorectomy in Young Women Carries Increased Mortality Risk

We were struck by the fact that instead of benefiting from the procedure, women age 45 or younger who undergo oophorectomy for the prevention of ovarian cancer are at a distinct long-term disadvantage as shown by a 70% increased mortality risk

by surmeno 2006-09-22 21:31 oophorectomy · risks · cardiovascular disease · hormones · hrts · surgery · hysterectomy · a1a

http://www.medscape.com/viewarticle/544956?rss - cached - mail it - history

Ibuprofen May Reduce Protective Effects of Aspirin

by surmeno 2006-09-20 20:24 risks · cardiovascular disease · drugs

http://www.medscape.com/viewarticle/544497?src=mp - cached - mail it - history

Could Heart Risks of Estrogen Replacement Be "Patched" Up?

very small 2003 study, one of many that helped document that there is indeed a difference between oral and transdermal in route-related effects

by surmeno 2006-09-07 23:33 cardiovascular disease · hrts · route · inflammation

http://www.acc.org/media/releases/highlights/2003/apr03/estrogen.htm - cached - mail it - history

What Type of Diet Is Best for Cardiovascular Prevention?

Also worth reading for an interesting discussion of how the widely publicized results of one portion of the WHI study, the diet arm, should be interpreted exactly opposite from the "take" publiziced in the popular media

by surmeno 2006-09-06 15:19 diet · cardiovascular disease · risks · nutrients · weight

http://www.medscape.com/viewarticle/543854_print - cached - mail it - history

Should Symptomatic Menopausal Women Be Offered Hormone Therapy?

Excellent evaluation of research related to risks: "We conclude that young, healthy symptomatic women should be offered the option of hormone therapy. There is clear evidence that hormone therapy improves vasomotor and urogenital symptoms and provides benefits to many women with sexual dysfunction and psychological disturbances related to estrogen deficiency. Taken together, the beneficial effects of hormone therapy for many younger women outweigh the risks and provide an overall improvement in quality of life. Thus, the fears of hormonal therapy in this setting do not seem to be justified. All hormonal therapy should be individualized in symptomatic women. This involves prescribing the regimen and dosage according to individual needs." (free signup required to read)

by surmeno 2006-08-20 00:12 hrts · risks · cancer · osteoporosis · cardiovascular disease · menopause

http://www.medscape.com/viewarticle/537095_print - cached - mail it - history

Beneficial Effects of Fish and Fish Oils in Cardiovascular Diseases

omega-3 fatty acids

by surmeno 2006-08-13 15:46 nutrition · diet · nutraceuticals · nutrients · cardiovascular disease

http://www.uspharmacist.com/index.asp?show=article&page=8_1035.htm - cached - mail it - history

Create A Diet Activity - NHLBI

Tool to construct a personalized diet following guidelines for cardiovascular disease rish control or treatment

by surmeno 2006-08-13 14:24 nutrition · diet · cardiovascular disease

http://nhlbisupport.com/cgi-bin/chd1/diet2.cgi - cached - mail it - history

Comparison of 4 Diets of Varying Glycemic Load on Weight Loss and Cardiovascular Risk Reduction in Overweight and Obese Young Ad

Small study that finds that making simple substitutions to replace high glycemic load items with lower glycemic index ones can lead to weight loss and improvement in cardiovascular disease risk markers.

by surmeno 2006-07-25 12:43 nutrition · diet · weight · cardiovascular disease

http://archinte.ama-assn.org/cgi/content/short/166/14/1466 - cached - mail it - history

Metabolic Syndrome May Predict Breast Cancer Recurrence

Metabolic syndrome, especially if associated with elevated testosterone, is "an important prognostic factor" in the recurrence of breast cancer,

by surmeno 2006-07-19 11:17 cancer · hormones · hrts · risks · cardiovascular disease · weight · metabolism

http://www.medscape.com/viewarticle/540794?src=mp - cached - mail it - history

Endocrinologists' Guidelines for the Diagnosis and Treatment of Menopause

This is simply the best article on the entire topic EVER: complete, full of research analysis, of impeccable credibility. Read this one article first: it's a whole education in itself. Really.

by surmeno 2006-07-17 22:02 hormones · hrts · osteoporosis · drugs · cancer · research · hysterectomy · cardiovascular disease · menopause · testosterone · risks · interactions · brain · lipids · cardiolipids · cholesterol · whi · progesterone · nutraceuticals · route · ssri · breast · soy · a1a

http://www.medscape.com/viewarticle/540531_print - cached - mail it - history

NEJM -- Risk-Benefit Profiles of Raloxifene for Women

"For now, there is no magic bullet that can reduce the risks of major health problems related to estrogens and aging without introducing other potentially serious health concerns." Good article summarizing hrt risks and benefits in general, not just related to SERMs

by surmeno 2006-07-13 12:37 hrts · osteoporosis · drugs · cardiovascular disease · cancer · risks · serm

http://content.nejm.org/cgi/content/full/355/2/190 - cached - mail it - history

Welcome to the UCSD Statin Study

Good coverage of statin effects as well as other important health measures

by surmeno 2006-06-30 17:59 drugs · cardiovascular disease

http://medicine.ucsd.edu/ses/ - cached - mail it - history

Coronary Heart Disease Events Associated with Hormone Therapy

Hormone therapy reduces the risk of CHD events in younger postmenopausal women. In older women, HT increases, then decreases risk over time.

by surmeno 2006-06-07 19:59 hrts · hormones · cardiovascular disease

http://www.medscape.com/viewarticle/532932_print - cached - mail it - history

Important Safety Information on Evista (raloxifene hydrochloride)- For Health Professionals - For the Public - Eli Lilly Canada Inc.

by surmeno 2006-05-31 19:53 hrts · hormones · osteoporosis · cancer · cardiovascular disease · serm

http://www.hc-sc.gc.ca/dhp-mps/medeff/advisories-avis/prof/2006/evista_hpc-cps_e.html - cached - mail it - history

Tibolone and HRT Boost Carotid Intima-Media Thickness

"given unexplained inconsistencies in trial outcomes" and other issues, the study does not support the conclusion that either treatment worsens atherosclerosis progression. [important to note that this only deals with Prempro, not any of the transdermals or estrogen alone-Framboise]

by surmeno 2006-04-27 15:21 cardiovascular disease · interactions · hormones · hrts

http://www.medscape.com/viewarticle/530068?src=mp - cached - mail it - history

Metabolic Syndrome in Women with Polycystic Ovary Syndrome?

PCOS was associated with an 11-fold increased risk of MS when compared with controls.--free registration required to read

by surmeno 2006-04-27 15:13 pcos · cardiovascular disease · insulin resistence · metabolism · diet · nutrition · cardiolipids

http://www.medscape.com/viewarticle/529294?src=mp - cached - mail it - history

FDA Safety Changes: Naprosyn/Anaprox and Other Prescription...

Many of these are used in post-narcotic pain relief after a hyst--right when we are already more susceptible to clots due to the surgery and/or initiation of hrt

by surmeno 2006-04-19 23:01 warning · drugs · interactions · cardiovascular disease

http://www.medscape.com/viewarticle/530229_print - cached - mail it - history

ge-Adjusted Long-term Estrogen Therapy.

An excellent reference that reviews the mechanisms of effects of hrts on osteoporosis, cardiovascular disease, blood clots, and breast cancer, and spells out the situation in very clear statements with pertinent comments on route and hrt-type selection. Also discusses the conclusions of the WHI study in the context of other known hormone physiology and research

by surmeno 2006-04-06 18:10 hormones · hrts · cancer · osteoporosis · news · survival · whi · cardiovascular disease

http://www.medscape.com/viewarticle/523851_print - cached - mail it - history