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Bill Hooker, member since Jan 4, 2006
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by sennoma 2009-12-24 16:35 lostart · scienceasabusiness · scienceisasnakepit · management
http://pbeltrao.blogspot.com/2009/12/name-that-lab.html?showComment=1261690523808_AIe9_BG7y_iu2nXOCXBLMqzVXdxPjjgBaoja4l... - cached - mail it - history
NIH grants vs. investigator age
by sennoma 2009-12-13 12:12 scienceisasnakepit · science.numbers · science.funding
http://metamodern.com/2009/11/27/great-science-great-scientists-and-icons/?utm_source=feedburner&utm_medium=feed&utm_cam... - cached - mail it - history
by sennoma 2009-09-27 20:23 opendata · openscience · scienceisasnakepit · scholarlycommunication
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0007078 - cached - mail it - history
After more than 40 years of full-time research in developmental biology and genetics, I wrote my first grant and showed it to those experienced in grantsmanship. They advised me my application would not succeed. I had explained that we didn't know what experiments might deliver, and had acknowledged the technical problems that beset research and the possibility that competitors might solve problems before we did. My advisors said these admissions made the project look precarious and would sink the application. I was counselled to produce a detailed, but straightforward, program that seemed realistic—no matter if it were science fiction. I had not mentioned any direct application of our work: we were told a plausible application should be found or created. I was also advised not to put our very best ideas into the application as it would be seen by competitors—it would be safer to keep those ideas secret.
by sennoma 2009-09-16 09:59 scienceisasnakepit
http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000197 - cached - mail it - history
If you are an editor, author, reviewer, or reader of medical journals, or if you depend on your doctor or health care provider getting unbiased information from medical journals, then the 1,500 documents now hosted on the PLoS Medicine Web site [1] should make you very concerned and angry. Because, quite simply, the story told in these documents amounts to one of the most compelling expositions ever seen of the systematic manipulation and abuse of scholarly publishing by the pharmaceutical industry and its commercial partners in their attempt to influence the health care decisions of physicians and the general public.
by sennoma 2009-09-10 01:35 scienceisasnakepit · ghostwriting
http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1000156 - cached - mail it - history
Many researchers are ignoring a 2005 requirement that they register proposed clinical trials in a government database as a condition for publishing their results in medical journals. And the journals are publishing the papers anyway, a new study reveals. The study, a review of 323 articles published last year in leading medical journals, found that only 147 of the clinical trials — 45.5 percent — were properly registered before the end of the trial in a way that clearly stated the main outcomes being assessed. Even among the articles that were registered, almost a third had discrepancies between the outcomes described in the registry and the ones ultimately reported. Of the trials that were not registered properly, 89 — more than half — were never entered in the National Institutes of Health’s clinical trials registry. The report appears in the Sept. 2 issue of The Journal of the American Medical Association.
by sennoma 2009-09-05 22:26 clinicaltrials · scienceisasnakepit
http://www.nytimes.com/2009/09/08/health/08aware.html?_r=1 - cached - mail it - history
by sennoma 2009-08-22 08:37 scienceisasnakepit
http://scienceblogs.com/ethicsandscience/2009/08/medical_ghostwriting_and_the_r.php - cached - mail it - history
by sennoma 2009-08-15 12:03 scienceisasnakepit
http://www.rin.ac.uk/node/680 - cached - mail it - history
by sennoma 2009-07-22 00:59 scienceisasnakepit
http://scienceblogs.com/ethicsandscience/2009/07/university_of_alabama_research.php - cached - mail it - history
Some of the salaries look very attractive, but what these surveys never indicate is the low, low probability of ever attaining any such position.
by sennoma 2009-07-12 16:02 scienceisasnakepit
http://www.phds.org/jobs/salary-information - cached - mail it - history
by sennoma 2009-07-09 00:27 lostart · scienceisasnakepit
http://scienceblogs.com/ethicsandscience/2009/07/how_to_discourage_scientific_f.php - cached - mail it - history
by sennoma 2009-07-09 00:26 lostart · scienceisasnakepit
http://scienceblogs.com/ethicsandscience/2009/07/fraud_rehabilitation_and_the_p.php - cached - mail it - history
Based on theoretical reasoning it has been suggested that the reliability of findings published in the scientific literature decreases with the popularity of a research field. Here we provide empirical support for this prediction. We evaluate published statements on protein interactions with data from high-throughput experiments. We find evidence for two distinctive effects. First, with increasing popularity of the interaction partners, individual statements in the literature become more erroneous. Second, the overall evidence on an interaction becomes increasingly distorted by multiple independent testing.
by sennoma 2009-06-24 13:57 scienceisasnakepit · misconduct
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005996 - cached - mail it - history
I was on Friday at the Royal Society, speaking at the annual seminar for learned societies held by Wiley-Blackwell. There were a number of interesting presentations, not least that from Gavin Sharrock on publishing ethics. His theme was how ethics had risen to become a much more important issue for publishers than it had been only a few years ago, with increases in the number of cases of malpractice, and of retractions of journal articles. The Committee on Publication Ethics (COPE) is doing valuable work in this area, and most publishers now have established procedures for dealing with such problems. But I had not realised that retractions at Wiley-Blackwell are now running at more than one a week. Publication ethics are a matter not just for publishers, of course, and they are at least mentioned in many of the codes of practice for research that are now proliferating (see for example the draft code recently issued by the UK Research Integrity Office). One of the points made in discussion by journal editors was that when problems of this kind arise, they can find themselves involved in many different sets of procedures, run by research funders or institutions, or in some parts of the world in formal legal proceedings. The relationships between these different sets of procedures can be highly complex, and also, of course, time cosuming. This is an issue that is going to have to be addressed if the number of cases conntinues to rise
by sennoma 2009-06-22 05:25 scienceisasnakepit
http://www.rin.ac.uk/node/653 - cached - mail it - history
by sennoma 2009-06-02 21:50 postdocproblem · femalescienceprofessor
http://science-professor.blogspot.com/2009/06/p-mentoring-2.html - cached - mail it - history
by sennoma 2009-06-02 21:49 postdocproblem · femalescienceprofessor
http://science-professor.blogspot.com/2009/06/postdoc-mentoring.html - cached - mail it - history
by sennoma 2009-05-30 18:10 postdocproblem · scienceisasnakepit · davidgoodstein
http://www.its.caltech.edu/~dg/crunch_art.html - cached - mail it - history
A pooled weighted average of 1.97% (N = 7, 95%CI: 0.86–4.45) of scientists admitted to have fabricated, falsified or modified data or results at least once –a serious form of misconduct by any standard– and up to 33.7% admitted other questionable research practices. In surveys asking about the behaviour of colleagues, admission rates were 14.12% (N = 12, 95% CI: 9.91–19.72) for falsification, and up to 72% for other questionable research practices. Meta-regression showed that self reports surveys, surveys using the words “falsification” or “fabrication”, and mailed surveys yielded lower percentages of misconduct. When these factors were controlled for, misconduct was reported more frequently by medical/pharmacological researchers than others. Considering that these surveys ask sensitive questions and have other limitations, it appears likely that this is a conservative estimate of the true prevalence of scientific misconduct.
by sennoma 2009-05-29 18:34 scienceisasnakepit
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005738 - cached - mail it - history
Music to my ears: "new responsibilities were announced for 'senior authors'. These responsibilities include ensuring that the original data described in the study are preserved and retrievable for reanalysis, confirming that the data presented in the manuscript are representative of the original data collected, and anticipating and minimizing any obstacles to the sharing of data, reagents, materials or algorithms described in the published work."
by sennoma 2009-05-26 13:23 scienceisasnakepit · scholarlycommunication
http://blogs.nature.com/nautilus/2009/05/nature_immunology_on_authorshi_1.html - cached - mail it - history
A frantic grant-writing effort that has consumed biomedical research scientists this spring came to an end last week, resulting in a huge pile of new applications—more than 10 times larger than expected—to be reviewed by the National Institutes of Health (NIH). After this enthusiastic response, there will be many disappointed applicants: The rejection rate could run as high as 97%.
by sennoma 2009-05-16 02:35 scienceisasnakepit
http://www.sciencemag.org/cgi/content/summary/324/5929/867-a - cached - mail it - history
by sennoma 2009-05-14 15:18 scienceisasnakepit · corruption
http://www.monbiot.com/archives/2009/05/12/captive-knowledge - cached - mail it - history
by sennoma 2009-05-14 14:34 scienceisasnakepit · oaos.examples
http://tierneylab.blogs.nytimes.com/2009/05/12/do-scientists-compete-unethically - cached - mail it - history
Investigators of scientific misconduct have had their hands full in recent months. So far this year, a regional hospital in western Massachusetts has announced the discovery of what may be the biggest case of research fraud in history, scientists in Texas have used a new computer algorithm to uncover thousands of apparently plagiarized papers in peer-reviewed journals and a congressional subcommittee questioned the consistency of institutional and independent review boards (IRBs) that oversee clinical trials
by sennoma 2009-05-08 22:29 scienceisasnakepit · misconduct · oaos.need
http://www.nature.com/nm/journal/v15/n5/full/nm0509-469a.html - cached - mail it - history
by sennoma 2008-08-08 11:18 postdocproblem · science.is.doomed
http://www.scienceprogress.org/2008/08/its-the-money-stupid/ - cached - mail it - history
by sennoma 2008-07-06 01:15 postdocproblem
http://friendfeed.com/e/33bc1ecf-8045-495e-8972-6c382fd0ce0f/Plight-of-the-Postdoc/ - cached - mail it - history
by sennoma 2008-07-06 01:15 postdocproblem
http://heather.cs.ucdavis.edu/itaa.real.html - cached - mail it - history
by sennoma 2008-07-06 01:15 postdocproblem
http://bigpicture.typepad.com/comments/2004/12/losing_our_inte.html - cached - mail it - history
by sennoma 2007-07-17 02:38 postdocproblem · science.is.doomed
http://www.the-scientist.com/news/home/53370/ - cached - mail it - history
by sennoma 2007-07-08 23:53 postdocproblem
http://www.nap.edu/books/0309069963/html/ - cached - mail it - history
by sennoma 2007-07-02 18:23 postdocproblem
http://sciencecareers.sciencemag.org/career_development/previous_issues/articles/1820/thanks_for_the_great_postdoc_barga... - cached - mail it - history
by sennoma 2007-05-31 00:47 postdocproblem
http://www.nationalpostdoc.org/site/c.eoJMIWOBIrH/b.1388059/k.DBBE/NPA_Home.htm - cached - mail it - history
by sennoma 2007-05-24 12:58 blogs · postdocproblem · science.is.doomed
http://postdoccarnival.blogspot.com/ - cached - mail it - history
by sennoma 2007-05-01 22:21 postdocproblem
http://seejanecompute.blogspot.com/2007/04/to-stay-or-go-part-1-framing-issues.html - cached - mail it - history
by sennoma 2007-05-01 22:20 postdocproblem
http://labcoats.blogspot.com/2007/04/are-phds-worth-it.html - cached - mail it - history
by sennoma 2007-04-28 14:41 postdocproblem · science.is.doomed
http://www.mja.com.au/public/issues/186_06_190307/letters_190307_fm-5.html - cached - mail it - history
by sennoma 2007-04-19 22:36 postdocproblem · fraudinscience
http://helpychalk.blogspot.com/2007/04/impact-of-faked-scientific-data.html - cached - mail it - history
by sennoma 2007-04-12 19:07 postdocproblem
http://biocurious.com/are-there-too-many-scientists - cached - mail it - history
Acknowledging the hierarchy -- and the power you wield as someone near the top of it -- is in tension with maintaining the claim that you got to your position near the top purely on the merits. If you acknowledge that some of you success had to do with help you may have gotten (of a sort that you are not inclined to give to others -- 'cause if they're good enough, they don't need your help), or that some of it may have been luck, then you can't take your esteemed position as conclusive evidence that you're really that good. Indeed, you might be in a position where you'd have to acknowledge that others who may be just as good as you (or better) are out there and unrecognized. You might have to come to grips with the idea that you cannot indefinitely defend you position at the top, at least not on the basis of your merit alone.
by sennoma 2007-04-09 11:51 postdocproblem
http://scienceblogs.com/ethicsandscience/2007/04/hierarchy_meritocracy_the_blog.php - cached - mail it - history
by sennoma 2007-04-08 14:42 postdocproblem
http://ask.metafilter.com/60164/Is-passion-with-average-competence-enough-for-a-research-career - cached - mail it - history
The Kitten Herding Problem notwithstanding, we really do need a union.
by sennoma 2007-04-03 11:13 postdocproblem
http://k8grrl.blogspot.com/2007/03/sexism-in-science-organize-organize.html - cached - mail it - history
by sennoma 2007-03-24 12:58 lostart · science · postdocproblem
http://scienceblogs.com/thusspakezuska/2007/03/life_as_a_leak_part_2.php - cached - mail it - history
see also http://www.seedmagazine.com/news/2007/03/scientific_method_relationship.php
by sennoma 2007-03-20 21:31 postdocproblem · science · networks
http://mapofscience.com/ - cached - mail it - history
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