• Does the manuscript apply under the NIH Public Access Policy? • Which NIH grant awards supported the manuscript? Use the NIH Grants Lookup Tool to confirm grant award numbers. • Which journal will the manuscript be submitted to? • Which method of submission does the journal fall under? See the NIH chart on submission methods. • If a Method C or D form of submission journal, which author will be assigned as the responsible author for the review and approval tasks? See the short video: Approving Submission of an Article to PubMed Central which outlines the process for authors in response to an email from NIHMS asking for approval of a submission done by a publisher or third party. • Which author will be responsible for making sure that the work has a PMCID within three months post publication of the manuscript, and notifying all authors and PIs associated with the manuscript of the most current means of documentation of compliance with the NIH Policy (“PMC Journal – In Process,” or NIHMS ID) until the PMCID is assigned?

Increasingly, scientific breakthroughs will be powered by advanced computing capabilities that help researchers manipulate and explore massive datasets. The speed at which any given scientific discipline advances will depend on how well its researchers collaborate with one another, and with technologists, in areas of eScience such as databases, workflow management, visualization, and cloud computing technologies. In The Fourth Paradigm: Data-Intensive Scientific Discovery, the collection of essays expands on the vision of pioneering computer scientist Jim Gray for a new, fourth paradigm of discovery based on data-intensive science and offers insights into how it can be fully realized.