Blueprint is a CSS framework, which aims to cut down on your CSS development time. It gives you a solid CSS foundation to build your project on top of, with an easy-to-use grid, sensible typography, and even a stylesheet for printing.

Prototype is a JavaScript framework that aims to ease development of dynamic web applications. Featuring a unique, easy-to-use toolkit for class-driven development and the nicest Ajax library around, Prototype is quickly becoming the codebase of choice for web application developers everywhere.

Building upon the wonderful Prototype JavaScript library, script.aculo.us provides you with some great additional ingredients to mix in.