A pilot without a map can locate an airport by first finding a nearby landmark, like a big river, and then searching for the airport.
New research from the University of Wisconsin School of Medicine and Public Health (SMPH) and Scripps Research Institute shows how the astonishingly powerful botulinum toxin uses a similar strategy to latch onto nerve cells, the first step in inactivating them.
The research helps explain how the toxin first attaches to a receptor on the surface of a nerve cell, then looks for a second type of receptor that is nearby. Once the toxin links to this second receptor, it can enter the nerve cell and break a protein needed to deliver molecules that can signal other nerve cells.
by
kysoh
2006-12-13 22:28
eurekalert
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diseases
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bacteria
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health
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medicine