Spyder (previously known as Pydee) is a free open-source Python development environment providing MATLAB-like features in a simple and light-weighted software, available for Windows XP/Vista/7, GNU/Linux and MacOS X.

Purity is a Python library for Pure Data dynamic patching. The idea is to be able to harness the power of Pure Data for audio programming without having to use its graphical interface. Python's clear and intuitive syntax can be used with profit in order to create intricate patches with advanced string handling, graphical user interfaces and asynchronous network operations. Purity uses Twisted, an event-driven Python framework.

The goal is to create a basic game prototyping sandbox built around open source software free for commercial use.

A flat file web publishing tool

MongoDB is a high-performance, open source, schema-free document-oriented database

Static Website Generator using Django Templates extended with Page Context Variables and Site Templates supports Plugins

PyOpenCL lets you access the OpenCL parallel computation API from Python

Pynomo is a program to create (pdf) nomographs (nomograms) using Python interpreter. A nomograph (nomogram) is a graphical solution to an equation.

Werkzeug started as a simple collection of various utilities for WSGI applications and has become one of the most advanced WSGI utility modules. It includes a powerful debugger, fully featured request and response objects, HTTP utilities to handle entity tags, cache control headers, HTTP dates, cookie handling, file uploads, a powerful URL routing system and a bunch of community contributed addon modules. Werkzeug is unicode aware and doesn't enforce a specific template engine, database adapter or anything else. It doesn't even enforce a specific way of handling requests and leaves all that up to the developer.