«Deep brain stimulation with electrical pulses may offer hope for patients trapped in a minimally conscious state.»

«Science Daily — In work published in the Proceedings of the National Academy of Sciences, a research team led by a Brown University neuroscientist describes groundbreaking recordings of activity in two brain regions during deep sleep. ~ The “dialogue” they captured occurred between the hippocampus and the neocortex, areas of the brain where scientists believe memories are made and stored. The findings were startling. ~ Researchers found that electrical activity in the brain cells of sleeping mice wasn’t completely random, the conclusion of past research. Instead, the team found that the slow and regular firing of excitatory cells in the neocortex was echoed a fraction of a second later in the hippocampus. The echo of cortical activity was different in the three parts of the hippocampus. Excitatory cells in the dentate gyrus showed a strong echo, while CA3 region cells showed a weak echo. Cells in the CA1 region responded in reverse, quieting down when the cortex was active.»

«[...] The protective effect of taurine was preserved under the blockade of inhibitory GABA(A) and glycine receptors. It is suggested that taurine may rescue the mechanisms of hippocampal synaptic plasticity by improving mitochondrial function under hyperammonemic conditions.»

«[...]~ Despite its period of invisibility, hysteria never vanished — or at least that is what many doctors say. ~[...]»

«[...] We tested 12 neuroleptic compounds and found that of these, the antipsychotic haloperidol and the mood stabilizer valproic acid most effectively inhibit Toxoplasma growth in vitro. Valproic acid inhibited the parasite at a concentration below that found in the cerebrospinal fluid and blood of individuals being treated with this medication and displayed synergistic activity with haloperidol and with trimethoprim, an antibiotic commonly used to treat Toxoplasma infections.Several medications used to treat schizophrenia and bipolar disorder have the ability to inhibit the in vitro replication of T. gondii.»

«Description:: GABAergic mechanism of action: inhibitor of GABA-transtransaminase. Significant suppression of serum cortisol. Weight gaining effects. Investigated in the treatment of choreatic syndromes. Clinical trials in the management of psychoses. Substantial antimanic effect reported. Studied for migraine prophylaxis. Plasma half-life of sodium valproate in healthy subjects about 15 hours. Mean half-life of unbound valproic acid in neonates 6. 7 up to 34. 2 hours. Terminal half-life in adult healthy subjects 16 ± 3 hours. T 1/2 is reduced in patients treated with other anticonvulsant drugs. [...]»

«Everything you thought you knew about migraine headaches — except that they are among the worst nonfatal afflictions of humankind — may be wrong. At least that’s what headache researchers now maintain. From long-maligned dietary triggers to the underlying cause of the headaches themselves, longstanding beliefs have been brought into question by recent studies. ~ [...]»

«Here at OHSU's Department of Neurological Surgery we have developed a helpful questionnaire for the diagnosis and treatment of patients suffering from varies types of trigeminal neuralgia.»

«Herpes zoster, colloquially known as shingles, is the reactivation of varicella zoster virus, leading to a crop of painful blisters over the area of a dermatome. In Italy and in Malta, it is sometimes referred to as St. Anthony's fire. It occurs very rarely in children and adults, but its incidence is high in the elderly (over 60), as well as in any age group of immunocompromised patients. It affects some 500,000 people per year in the United States. Treatment is generally with antiviral drugs such as aciclovir. Many patients develop a painful condition called postherpetic neuralgia which is often difficult to manage.»