jkniiv's Feed

Costochondritis

jkniiv — Sun, 13 Jan 2008 12:48:00 -0500

«Costochondritis is characterized by pain and tenderness in the cartilage that connects the ribs to the breastbone. It is the most common cause of chest wall pain and primarily affects adults over 40 years. When swelling accompanies the pain and tenderness, the condition is called Tietze syndrome. Tietze syndrome is rare and generally affects people under the age of 40.» Tagged by jkniiv under costochondritis, @article, pain, cartilage, rib, breastbone, sternum, chest pain, chest, medicine, @y: 2007, @date:2007m08,

Costochondritis

jkniiv — Sun, 13 Jan 2008 12:44:00 -0500

«Costochondritis is a condition that causes chest pain due to inflammation of the cartilage and bones in the chest wall. Also called Tietze's Syndrome, costochondritis occurs when there is inflammation at the junction of the rib bone and breastbone (sternum). At this junction, there is cartilage joining these bones. This cartilage can become irritated and inflamed. Depending on the extent of the inflammation, costochondritis can be quite painful.» Tagged by jkniiv under costochondritis, @article, inflammation, chest pain, chest, pain, cartilage, bone, breastbone, sternum, medicine, @y: 2007, $date:2007m09,

BBC NEWS | Health | Electrical pulses 'rouse' patient

jkniiv — Wed, 01 Aug 2007 02:29:00 -0400

«Deep brain stimulation with electrical pulses may offer hope for patients trapped in a minimally conscious state.» Tagged by jkniiv under @news, @research, deep brain stimulation, brain injury, brain, recovery, treatment, neurology, medicine, $date:2007m08, @y: 2007,

BBC NEWS | Health | Healthy weight link to longevity

jkniiv — Fri, 20 Jul 2007 04:28:00 -0400

«Keeping a healthy weight may help people live longer by limiting brain exposure to insulin, say US scientists.» Tagged by jkniiv under @news, @research, weight, metabolism, insulin, longevity, life extension, brain, irs2, dementia, medicine, $date:2007m07, @y: 2007,

BBC NEWS | Health | Protein mutations link to autism

jkniiv — Thu, 28 Jun 2007 10:57:00 -0400

«Scientists have discovered how mutations in two key proteins may lead to autism.» Tagged by jkniiv under @news, @research, autism, neuroligin, neuroligin-1, nlgn1, neuroligin-2, nlgn2, neuron, nerve, cell, link, synapse, simon baron-cohen, medicine, $date:2007m06, @y: 2007,

BBC NEWS | Health | Autism symptoms reversed in lab

jkniiv — Wed, 27 Jun 2007 11:24:00 -0400

«Symptoms of mental retardation and autism have been reversed for the first time in laboratory mice.» Tagged by jkniiv under @news, @research, autism, fragile x syndrome, fmr1, pak, enzyme, mouse model, mouse, treatment, medicine, $date:2007m06, @y: 2007,

Thermoregulation - Wikipedia, the free encyclopedia

jkniiv — Tue, 22 May 2007 10:58:00 -0400

«Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when temperature surrounding is very different. This process is one aspect of homeostasis: a dynamic state of stability between an animal's internal environment and its external environment (the study of such processes in zoology has been called ecophysiology or physiological ecology). If the body is unable to maintain a normal temperature and it increases significantly above normal, a condition known as hyperthermia occurs. The opposite condition, when body temperature decreases below normal levels, is known as hypothermia. ~[...]» Tagged by jkniiv under thermoregulation, @definition, body temperature, temperature, hypothermia, hyperthermia, medicine, $wikipedia.en,

Temperature of a Healthy Human (Body Temperature)

jkniiv — Tue, 22 May 2007 10:56:00 -0400

«The normal core body temperature of a healthy, resting adult human being is stated to be at 98.6 degrees fahrenheit or 37.0 degrees celsius. Though the body temperature measured on an individual can vary, a healthy human body can maintain a fairly consistent body temperature that is around the mark of 37.0 degrees celsius. ~[...]» Tagged by jkniiv under @resource, human, body temperature, temperature, measurement, thermoregulation, medicine,

eMedicine - Dyshidrotic Eczema : Article by Anne E Burdick, MD, MPH

jkniiv — Sun, 20 May 2007 09:17:00 -0400

«Background: Dyshidrotic eczema is a recurrent or chronic relapsing form of vesicular palmoplantar dermatitis of unknown etiology. Dyshidrotic eczema also is termed pompholyx, which derives from cheiropompholyx, which means "hand and bubble" in Greek.» Tagged by jkniiv under @article, dyshidrotic eczema, dyshidrosis, pompholyx, eczema, dermatitis, atopic dermatitis, atopy, medicine, $date:2006m01, @y: 2006,

Is this recently characterized gastrointestinal pathogen responsible for rising rates of inflammatory bowel disease (IBD) and IBD associated autism in Europe and the United States in the 1990s?

jkniiv — Wed, 25 Apr 2007 12:49:00 -0400

«In 2006, a pathogenic variant of the common intestinal organism Blastocystis was discovered in patients who were experiencing chronic gastrointestinal symptoms. Most species of Blastocystis inhabit humans with no symptoms. The discovery of a pathogenic variant of Blastocystis is significant, because Blastocystis is related to Entamoeba, a similar organism with pathogenic variants that kill over 100,000 people each year. Recent research has shown that Blastocystis infections may be undetectable using existing clinical methods. Medical case reports from the Middle East, Europe, and United States suggest that infection with this variant may already be widespread and misdiagnosed as one of several functional disorders. HYPOTHESIS: A more virulent or transmissible type of Blastocystis emerged in the Middle East in the 1980's, and was transmitted to Europe and the United States by military and more significantly vacation and business travel. The lack of adequate tests made it impossible to detect the infection. Transmission to the larger population resulted in rising inflammatory bowel disease (IBD) rates in Europe in the 1990's. The relationship between IBD and autism is explored, along with the possibility that the same pathogen causes both conditions. SUPPORTING DATA: Serological and epidemiological findings are presented supporting the hypothesis. Blastocystis survives sewage treatment, shows low host specificity, and can be spread by many animals. Several communities which have been studied due to high autism rates are located close to rivers which receive large quantities of sewage effluent, such as South Thames (England), Olmsted County (Minnesota, USA) and many communities in Oregon (USA). CONCLUSIONS: Scientists from other countries represent the first line of defense against emerging infectious diseases, but their publications on Blastocystis are not well known in the United States and Europe. With the publication of corroborating research by Western scientists in core scientific journals, it is hoped that an appropriate response from the public health system will be forthcoming. Investigation into the existence of infection in the groups mentioned with sensitive and specific tests should be performed. Such tests could include a serum antibody test and a Polymerase Chain Reaction test specific to the pathogenic variant.» Tagged by jkniiv under @research-abstract, blastocystis, blastocystis infection, entamoeba, parasite, gastrointestinal disease, inflammatory bowel disease, ibd, autism, europe, united states of america, usa, medical hypotheses, medicine, @date:2007m03, @y: 2007, $pubmed/hubmed,

eMedicine - Lactic Acidosis : Article by Sat Sharma, MD, FRCPC, FACP, FCCP, DABSM

jkniiv — Thu, 08 Feb 2007 06:50:00 -0500

«Background: By the turn of the 20th century, it had become apparent that patients who are critically ill could exhibit metabolic acidosis unaccompanied by elevation of ketones or other measurable anions. In 1925, Clausen identified the accumulation of lactic acid in blood as a cause of acid-base disorder. Several decades later, Huckabee's seminal work firmly established that lactic acidosis frequently accompanies severe illnesses and that tissue hypoperfusion underlies the pathogenesis. In their classic 1976 monograph, Cohen and Woods classified the causes of lactic acidosis according to the presence or absence of adequate tissue oxygenation. ~ [...]» Tagged by jkniiv under @article, lactic acidosis, lactic acid, lactate, acidosis, metabolism, medicine, $date:2006m10, @y: 2006,

Evidence for a trigger function of valproic acid in xenobiotic-induced hepatotoxicity.

jkniiv — Wed, 13 Dec 2006 10:17:00 -0500

«[...] These findings indicate that valproic acid affects hepatocellular defence mechanisms and suggest that a predisposition of hepatocytes to oxidative stress may play a role in the fatal hepatotoxicity of valproic acid in epileptic patients.» Tagged by jkniiv under @research-abstract, valproic acid, valproate, toxicity, hepatotoxicity, hepatoprotection, n-acetylcysteine, oxidative stress, hepatic glutathione, glutathione, hepatic, liver, medicine, @y: 2000, $date:2000m08,

Megaloblastic Anemia And Hyperhomocysteinemia Possibly Secondary To Vitamin B-12 Due To Sodium Valproate

jkniiv — Tue, 28 Nov 2006 01:17:00 -0500

«Long-term administration of sodium valproate is associated with vitamin deficiencies ( 1 ). To our knowledge, sodium valproate induced vitamin B-12 deficiency in the adult population has never been reported in the literature. We present a patient with megaloblastic anemia and hyperhomocysteinemia due to vitamin B-12 deficiency secondary to sodium valproate.» Tagged by jkniiv under @article, sodium valproate, valproate, anticonvulsant, antiepileptic drug, aed, vitamin b12, homocysteine, hyperhomocysteinemia, anemia, medicine, @y: 2004,

Research by [Stenberg (Porkka-Heiskanen), T.]

jkniiv — Mon, 30 Oct 2006 12:43:00 -0500

Research by [Stenberg (Porkka-Heiskanen), T.] Tagged by jkniiv under @research, @resource, asperger's, adhd, arousal, sleep, motor neuron, finland, medicine,

Valproic acid adjunctive therapy for HIV-associated cognitive impairment: a first report.

jkniiv — Fri, 27 Oct 2006 08:22:00 -0400

«In vitro and animal model data demonstrate that valproic acid (VPA) can ameliorate HIV-associated neurotoxicity. The authors conducted a pilot 10-week placebo-controlled study of VPA 250 mg twice daily in 22 HIV-infected individuals with (n = 16) and without (n = 6) cognitive impairment. VPA was safe and well tolerated, with trends toward improved neuropsychological performance and brain metabolism in the impaired subjects.» Tagged by jkniiv under @research-abstract, valproic acid, valproate, hiv, neurotoxicity, aids, dementia, treatment, drug therapy, medicine, $date:2006m03, @y: 2006, $pubmed/hubmed,

Donepezil - Wikipedia, the free encyclopedia

jkniiv — Fri, 20 Oct 2006 02:50:00 -0400

«Donepezil, marketed under the trade name Aricept® (Eisai), is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a half life of about 70 hours, it can be taken once a day. Initial dose is 5 mg per day, which can be increased to 10 mg per day after an adjustment period of at least 4 weeks.» Tagged by jkniiv under donezepil, aricept, @definition, acetylcholine, acetylcholinesterase, cholinesterase inhibitor, alzheimer's disease, memory, cognition, medicine, $wikipedia.en,

Taurine rescues hippocampal long-term potentiation from ammonia-induced impairment.

jkniiv — Fri, 29 Sep 2006 09:45:00 -0400

«[...] The protective effect of taurine was preserved under the blockade of inhibitory GABA(A) and glycine receptors. It is suggested that taurine may rescue the mechanisms of hippocampal synaptic plasticity by improving mitochondrial function under hyperammonemic conditions.» Tagged by jkniiv under @research-abstract, taurine, hippocampus, neuroprotection, ammonia, neurology, medicine, @y: 2006,

Is Hysteria Real? Brain Images Say Yes - New York Times

jkniiv — Wed, 27 Sep 2006 11:47:00 -0400

«[...]~ Despite its period of invisibility, hysteria never vanished — or at least that is what many doctors say. ~[...]» Tagged by jkniiv under @article, hysteria, conversion disorder, functional disorder, brain imaging, spect, pet, psychiatry, neurology, medicine, $date:2006m09, @y: 2006,

MedlinePlus Herbs and Supplements: Chamomile (Matricaria recutita, Chamaemelum nobile)

jkniiv — Thu, 31 Aug 2006 07:42:00 -0400

«Chamomile has been used medicinally for thousands of years, and is widely used in Europe. It is a popular treatment for numerous ailments, including sleep disorders, anxiety, digestion/intestinal conditions, skin infections/inflammation (including eczema), wound healing, infantile colic, teething pains, and diaper rash. In the United States, chamomile is best known as an ingredient in herbal tea preparations advertised for mild sedating effects.» Tagged by jkniiv under @article, chamomile, medicine, medlineplus,

Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast.

jkniiv — Sun, 27 Aug 2006 09:50:00 -0400

«[...] Our studies thus reveal an unexpected metabolic deficiency in T. gondii and raise the question whether the close interaction of host mitochondria with the parasitophorous vacuole is connected to lipoate supply by the host.» Tagged by jkniiv under @research-abstract, toxoplasma gondii, alpha-lipoic acid, medicine, $date:2006m07, @y: 2006,